Can I Give My Dog SAM-e?

Can I Give My Dog SAM-e?S-Adenosyl methionine, or SAM-e, is a new but very promising supplement. It occurs naturally in your dog’s body, but perhaps enough isn’t being produced.

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SAM-e is good for the liver as well as arthritis. Everyone knows that dogs often have joint problems later in life. Taking these daily may make life easier.

So, this dietary supplement can be good for dogs. Though the FDA doesn’t regulate SAM-e, most experts are confident about S-Adenosyl’s powerful health benefits.

Can I Give My Dog SAM-e? Answer: Yes

Especially if there is a deficiency, admittedly difficult to know.

SAM-E can be a supplement for your dog. Some situations warrant adding naturally occurring chemicals. It’s especially true for canines suffering from liver or bone-related problems. There are quality SAM-e supplements made specifically for pets.

We give our oldest dog the product pictured above. It helps with joint stiffness and swelling.

For Fighting Osteoarthritis

Sadly, it’s a fact that many owners struggle to help their dogs with arthritis. The good news is that SAM-e usually works well as a natural treatment alternative. It’s a really great anti-inflammatory.

In fact, several studies have shown that its effectiveness is on-par with Celebrex and several NSAIDs but with less side-effects. Sam-e holds promise for pets.

Excellent for Liver Health

Liver function is a critical component of good canine health. Liver cells can become damaged when the organ is not producing enough SAM-e. That’s when supplementation for a dog becomes very important.

It could get Fido’s liver back to producing glutathione. S-Adenosyl may enable protein synthesis, liver cell replication and better movement (exit) of bile acids.

Not only can SAM-e prevent further damage, but it may even heal and repair cells! There are reasons to believe that it helps dogs with liver disease. Consult with a vet for such serious conditions.

Treating Dog Depression

SAM-e is such a great supplement because it promotes good health across the board. There are indications that it can also help with depression.

It’s not uncommon for a pet dog to feel down due to health-related issues. SAMe’s ability to alleviate depressive symptoms will be beneficial.

If it works, S-Adenosyl methionine is a much superior alternative to potentially dangerous SSRI’s. It’s way safer since it’s naturally occurring much like well-known Melatonin.

Dosage and Duration

You will not see results right away. Give SAM-e some time for your dog’s sake. It usually takes between 2 weeks and 1 month to begin kicking in. People tend to give up to easily if they don’t see much happening.

Stick with it and try not to skip any days. In the end, you may be pleasantly surprised at what SAM-e can do for your pet dog.

Dosing a dog for SAM-e is straightforward. A general rule of thumb is 10mg per pound of body weight. For 40 pounds, 400mg is sufficient. Provide it on an empty stomach for maximum absorption.

Conclusion on SAM-e

S-Adenosyl is a promising health supplement for dogs. Pets can take SAM-e for arthritis, improved liver function and depression. Dogs not producing enough of their own SAM-e may benefit. Follow dosing guidelines since too much SAM-e is problematic. Discuss any supplement use, including SAM-e, with a trusted vet.

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Dr. Stephanie Flansburg Cruz, a practicing vet, has reviewed and endorsed this article. She has 3 dogs of her own and cares about the welfare of all animals.


  1. Deb
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